Common skin bacteria found to produce skin-cancer killing molecule
A skin producing bacteria can help individuals protect against skin cancer, a new study suggests. The scientists described that a specific bacteria strain of Staphylococcus epidermidis secretes a chemical that eliminates harmful bacteria which have been depicted as responsible for infections.
"We have identified a strain of Staphylococcus epidermidis, common on healthy human skin, that exerts a selective ability to inhibit the growth of some cancers", says Richard Gallo, one of the authors on the study.
Researchers at the University of California San Diego exposed mice with tumors to Staphylococcus epidermidis bacteria and found that a molecule produced by the bacteria stopped the tumors from growing.
"This unique strain of skin bacteria produces a chemical that kills several types of cancer cells but does not appear to be toxic to normal cells", he told MedicalNewsToday. "In fact, we previously reported that some bacteria on our skin produce antimicrobial peptides that defend against pathogenic bacteria such as, Staph aureus", said Dr Gallo.
When the team investigated further, they found that 6-HAP blocked the activity of DNA polymerase, an enzyme required for the formation of DNA.
Russian Federation says reinstated by International Olympic Committee
Rodchenkov now lives in hiding in the United States. "The acrimony caused by Bach's mismanagement should be his undoing", Walden said.
Bakambu topples Aubameyang to become most expensive African footballer
Beijing kick off their Chinese Super League campaign on Sunday when they travel to Shandong Luneng. Now it is my turn to help the team".
Court rules EU-Morocco fishing pact can't include W Sahara
The Polisario Front independence movement and Morocco fought for control of the Western Sahara from 1974 to 1991 until an UN-brokered ceasefire.
According to Dr Gallo, 6-HAP prevents tumor growth by inhibiting DNA synthesis.
The skin bacteria is called the Propionibacterium acnes and is producing a protein named RoxP which has the role to shield skin cells against what is known as oxidative stress - a condition in which the cells are damaged and can transform into cancer cells.
Mice that received intravenous injections of 6-HAP every 48 hours over a two-week period experienced no apparent toxic effects, but when transplanted with melanoma cells, their tumour size was suppressed by more than 50 percent compared to controls.
Perhaps, the research findings of this study is bit different from the previous research.
Co-program leader and professor of microenvironment, metastasis and immunology, Ashani Weeraratna from the Wistar Institute's Melanoma Research Center, Philadelphia stated that, "It's clear that an understanding of the microbiome - the bacterial landscape, so to speak - is critical to harness the full potential of some of the outstanding immunotherapy we have available to treat cancers, like melanoma". "The next stage of this exciting work, will be to translate it to human clinical trials and show that this bacterially produced chemical can protect the host from skin cancers".
Recommended News
-
02 March 2018American Airlines, Qantas re-seek USA nod for joint venture
Since then co-operation between the airlines has, by economic necessity, retrenched, they say in today's application. The Fort Worth-based carrier estimates up to 180,000 new trips annually from the joint venture.
02 March 2018Red alert for snow
Travel and public transport disruption is expected, and hundreds of schools across the country have already been closed. However, a yellow "be aware" warning for snow - which covers much of the south east - no longer applies to Kent.
02 March 2018No Deal After White House Biofuels Meeting
Grassley also said he and Ernst have made it clear that a cap on RIN prices or a waiver credit for RINs would not be a win-win solution. -
Sporty Alfa Romeo Giulia, Stelvio and 4C specials at Geneva
Other features include an Alpine Hi-Fi system, Italia dashboard plaque, and Spider Italia sticker on the side of the vehicle . The NRING edition of the sedan and the SUV will be limited to just 108 units, one for each year of the history of Alfa Romeo.
02 March 2018People aren't happy with Kate Middleton's latest fashion decision
Well, yes, the meltynautes, the british royal family counts among its ranks a couple that continues to fascinate the world. However, given how Buckingham Palace have handled the rumours before, it seems unlikely that she will be welcoming two ...Arsene Wenger 'hopeful' Jack Wilshere will sign new contract
New signings Henrikh Mkhitaryan and Pierre-Emerick Aubameyang are both earning DOUBLE what the midfielder takes home too. And reports suggest the Gunners and Wilshere's team are miles apart in talks over a new deal. "It's progressing. -
02 March 2018Sea of Thieves' Latest Scale Test Kicks off This Weekend
It will let you even disguise yourself as a newbie and join an unsuspecting crew's maiden voyages. And he also hinted at another possible feature coming to the game - the ability to...paint?
02 March 2018Investors Purchase Large Volume of Call Options on Canadian Natural Resource (CNQ)
Dimensional Fund Advsrs Ltd Partnership holds 0.04% of its portfolio in Stepan Company (NYSE:SCL) for 1.04 million shares. Stifel Nicolaus upgraded Energy Transfer Partners, L.P. (NYSE:ETP) on Friday, August 5 to "Buy" rating.
02 March 2018Samsung S9, S9+: 50% of phones made in Vietnam
Samsung finally launched the Galaxy S9 but unlike previous events, this one at the Mobile World Congress was a little bit weird. The Galaxy S9 isn't due out for another couple weeks but that isn't stopping Samsung from collecting some early accolades. -
02 March 2018North Korea helping Syria manufacture chemical weapons, reports claim
Security Council missions on Thursday, but diplomats said Russian Federation did not attend. The country is not a signatory to the Chemical Weapons Convention.
02 March 2018Gun control debate: Trump to meet with key lawmakers Wednesday
There is broad bipartisan support for the measures. " We shouldn't be banning guns for law-abiding citizens", Ryan told reporters. Something must be done: Donald Trump has called on U.S. lawmakers to "go big" on legislation to prevent more school shootings.
02 March 2018Putin shows Florida getting nuked in mock video to boast new weapons
He said the new weapons would help ensure global stability and draw a line under attempts to weaken Russian Federation . All of the weapons are reportedly nuclear-powered, a feature that would significantly extend the range of the missiles.
