Bournemouth striker Jermain Defoe is in contention to play against his former club.
It has been a particularly tough period Pochettino's team as they have suffered in the Champions League, being knocked out at the Round of 16 stage after a loss against Juventus on Wednesday.
Eddie Howe wants his Bournemouth players to "focus on themselves" and not Tottenham Hotspur following their opponents' exit from the Champions League this week.
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Former Arsenal midfielder Paul Merson has told Sky Sports that player inexperience, and not Mauricio Pochettino's management, cost Tottenham Hotspur a place in the Champions League quarter finals. It will be important for the likes of Harry Kane, Christian Eriksen, and Dele Alli to lead the team since their energy will lift the side for this game. "The [Champions League] exit will have really hurt them, they were the best team for the majority of that game". The Cherries are in a relegation battle and with teams around them winning, they need points as well to ensure they survive.
Bournemouth manager Eddie Howe says there is too much at stake to enjoy watching matches. At home, Bournemouth are a unsafe side and I think they will show that again this weekend. I just think that they, I don't know if they understand. And Man United got absolutely slaughtered [in their 0-0 draw against Sevilla], but if Man United go and win against Seville they're through, job done. The Spurs are too good in terms of talent and I think they will bounce back strongly. "We have beaten some very good teams - the crowd get behind us and we make it very hard for opposing teams". This game should be a 1-0 or 2-0 win to Spurs.
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