Common cold
The scientists found they were able to block replication of several strains of the virus without human cells being affected.
Viruses typically "hijack" NMT from human cells to construct the capsid - or protein shell - to protect the virus genome.
In a paper published to Nature Chemistry, the team detailed its new molecule, which targets N-myristoyltransferase (NMT), a protein in human cells.
Much of the effort to cure the common cold is centered around targeting the genomes of the viruses that cause it.
Producing a traditional vaccine for the common cold has proved to be a futile exercise but researchers at Imperial College may have discovered a novel new way to target the common cold and prevent its ability to replicate.
Until now it has been virtually impossible to vaccinate against cold virus because the condition is made of up a large family of different strains.
"Even if the cold has taken hold, it still might help lessen the symptoms".
HP Envy and Elite PCs: Smallest convertible to widest curved all-in-one
HP rates this model for up to 12 hours and 45 minutes of usage, which we look forward to testing with the Laptop Mag Battery Test. HP Audio Stream has been baked in, too, allowing you to use the ENVY AiO's speakers as the Bluetooth output for your phone.
Team: Former Sen. Harry Reid undergoes cancer surgery
Reid underwent surgery in 2015 after he fell and injured his eye while exercising at his home in Henderson. He retired from the Senate in 2017 .
Denver Broncos RB De'Angelo Henderson avoids serious injury in auto crash
The 5-7, 208-pound running back rushed seven times for 13 yards and caught two passes for 36 yards and a touchdown in 2017. "He was taken to the hospital as a precaution and is at the team's facility preparing to participate in OTAs next week".
The drug is also hypothetically effective in dealing with polio and foot and mouth disease, which have similar viruses to the common cold.
Rather than attacking the virus itself, which comes in hundreds of versions, the treatment targets the human host. A newly tested molecule appears to offer real hope.
They're working on making a form of the drug that can be inhaled as a way to reduce any further risks or complications.
The research team included the labs of Professor Roberto Solari and Professor Seb Johnston at Imperial's National Heart & Lung Institute, Dr Aurelie Mousnier from Imperial and Queen's University Belfast, structural biologists at the University of York, and colleagues at the Pirbright Institute.
By inventing a novel way to combine the two, they created a molecule, codenamed IMP-1088, which is more than a hundred times more potent than previous molecules targeting the protein in humans.
Laboratory tests showed how an experimental drug stopped the rhinovirus - the predominant cause of the common cold - hijacking a human protein to build the protective shell, or "capsid". They found two compounds that seemed to work well together, so they combined them to make IMP-1088.
Recommended News
-
15 May 2018Palestinians Protest Opening Of US Embassy In Jerusalem
Jared Kushner , Trump's son-in-law and senior adviser, praised the president for following through on his election promise. Bush, objected in particular to past comments by both Jeffress and Hagee that were critical of the Roman Catholic Church.
15 May 2018Brazil name injured Neymar in World Cup squad
I don't want anyone to feel sorry for me, I've lived my dreams. "I am so sad to hear this", the 77-year-old tweeted. Who knows, maybe when the 2022 World Cup comes around, I will still be competing for a place on the team.
15 May 2018Children Rescued From Filthy Fairfield Home; Mother And Father Arrested
Neighbor Larry Magnaye said he had no idea there were 10 children living in the house across the street. I strive and I pride myself on being a good parent to my children, My husband has a lot of tattoos. -
15 May 2018New volcanic fissure in Hawaii opens; brings total to 19
The incident drained the lava lake of the volcano into the surrounding parts of the island and, since then, has only gotten worse. So far, some 40 homes and other buildings have been destroyed by the red-hot lava that has been flowing from the volcano.
15 May 2018Divinity Original Sin 2 Heads to Xbox Game Preview on May 16th
What's more, those who pre-order the game on the Xbox Live Marketplace, the entire first act will be available to play. The announcement trailer for the Xbox Game Preview cane be seen below.
15 May 2018Tyronn Lue to start Tristan Thompson in Game 2 vs. Celtics
Thompson played 21 minutes off the bench, totaling eight points and 11 rebounds, in Game 1. Tristan Thompson could be earning his way back into the Cavaliers' good graces, too. -
15 May 2018Columbia Police arrest protesters accused of unlawfully assembling
Glover asked those in attendance to support teachers and other unionized employees, frequently recounting Dr. Officers cited 10 protesters at the Iowa Capitol who gathered in and around the staff offices of Gov.15 May 2018Tiger Woods' biggest statement comes after play in bold step
He won the tournament by four shots and was greeted on the green by a hug from his wife Dowd, the mother of their four children. That was no problem because he had banked such a lead, matching Greg Norman's mark for low three-round total of 19 under.
15 May 2018Steven Gerrard's First Rangers Signing Is From The Premier League
The 29-year-old midfielder is also familiar with Scottish top flight football after previously spending three years at Falkirk between 2007 and 2010. -
15 May 2018Khloe Kardashian Posts the First-Ever Footage of Baby True on Instagram
Simpson, keeping alive a long-held rumor that Simpson is Khloe's father instead of the late Robert Kardashian. Unfortunately, with all the good also comes the bad, and at least one fan compared True with O.J.
15 May 2018Dead, Thousands Wounded As Israeli Forces Fire On Palestinian Protesters
Attendants handed out pretzels and mineral water. "Thank you, President Trump, for having the courage to keep your promises". Ivanka Trump helped declare the new embassy open and a plaque and seal were unveiled before the 800 guests at the ceremony.
15 May 2018A Brand New Weapon is Coming to Fortnite: Battle Royale
It will probably still have the same 3-shot burst and take medium ammo but we'll be able to tell you for certain tomorrow. The assault rifle with scope still has yet to receive an epic and legendary weapon, as well as the submachine gun.
